Pharmacological and Parenteral Therapies

The nurse must be able to safely administer medications and other therapeutics as well as differentiate between intended effects and side effects. The Pharmacological and Parenteral Therapies subcategory of the NCLEX-RN exam covers topics related to medication administration, injections, and infusions. This section covers blood product administration, dosage calculating, venous access, and other issues pertinent to medication and parenteral therapies.

The 25-week-gestation neonate is ordered to receive ampicillin 100 mg/kg/day intravenously divided into doses every 12 hours immediately after birth. The neonate weighs 745 grams. The pharmacy dispenses ampicillin in a 5 mL vial that contains 125 mg. How many milliliters will the nurse administer with each dose? Round your answer to the nearest tenth decimal.

  • Question Type:   Fill in the Blank
  • Difficulty: 6
  • Topics: Labor and Delivery Neonatal Care Routes of Administration Infection Medication and Blood Products Nursing Interventions Weight-Based Dosing

The 32-week-gestation, 1.9 kg neonate has been prescribed intravenous ampicillin for concerns for sepsis. The dose is 150 mg/kg/d divided into 2 doses administered over 15 minutes. The pharmacy dispenses the medication in a 5 mL vial that contains 250 mg of medication. At what rate will the nurse program the medication to infuse? Round your answer to the nearest tenth decimal.

  • Question Type:   Fill in the Blank
  • Difficulty: 7
  • Topics: Neonatal Care Routes of Administration Infection Medication and Blood Products Nursing Interventions Weight-Based Dosing

The nurse is providing education to the patient who is starting warfarin for treatment of a deep vein thrombosis (DVT). Which statements are included in teaching? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 7
  • Topics: Hematology/Oncology Medication and Blood Products Cardiovascular Patient Education

The nurse instructs the patient with diabetes mellitus to store prefilled insulin syringes in which location?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 7
  • Topics: Endocrine Medication and Blood Products Communication & Documentation Health Promotion Patient Education Routes of Administration

A child with “staring fits” is diagnosed with absence seizures. The nurse prepares patient education materials on which medication?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 5
  • Topics: Neurology Communication & Documentation Medication and Blood Products Nursing Interventions Patient Education Pediatrics Routes of Administration

The nurse receives a call from the patient with type 2 diabetes who has nausea, vomiting, and is eating less. Which statement by the patient indicates that further education is needed?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Endocrine Communication & Documentation Health Promotion Patient Education

The patient is undergoing placement of an antibiotic-impregnated central line catheter for vancomycin infusions. Which statements are true about this type of catheter? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 6
  • Topics: Medication and Blood Products Routes of Administration Health Care Quality Immunity Infection

The nurse is assisting the physician with insertion of a central venous catheter into the patient's left internal jugular vein. Into which position does the nurse place the patient? 

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 5
  • Topics: Cardiovascular Routes of Administration Disease Prevention Neurology Nursing Interventions

The nurse must reconstitute a medication for intravenous administration. Using a syringe, the nurse draws up an appropriate amount of diluent. Which action does the nurse should take next?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 4
  • Topics: Routes of Administration Medication and Blood Products Nursing Interventions

The nurse anticipates administering which medication to the patient with osteomyelitis? 

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 3
  • Topics: Medication and Blood Products Infection Musculoskeletal

The provider orders an infusion of 10mL/kg/hr for the patient who weighs 154 lbs. The nurse arranges the IV infusion pump to dispense which flow rate?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 5
  • Topics: Routes of Administration Weight-Based Dosing Medication and Blood Products Nursing Interventions

The nurse is caring for the patient with fever, chills, and a cough productive of green sputum. The chest X-ray shows a hazy opacity. The nurse checks the patient's medical history for sensitivity to which medication? 

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 3
  • Topics: Health Promotion Immunity Infection Medication and Blood Products Respiratory

The nurse is caring for the patient with intestinal obstruction who is receiving total parenteral nutrition (TPN). The nurse reviews which lab results to ensure the patient is tolerating the infusion? Select all that apply. 

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 8
  • Topics: Acid-Base Endocrine Fluid and Electrolytes Gastrointestinal Laboratory Studies Medication and Blood Products Routes of Administration

The pediatric patient is hospitalized for fever, nausea, vomiting, and diarrhea. Capillary refill is >2 seconds. The nurse anticipates an order for which intravenous infusion?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 4
  • Topics: Pediatrics Fluid and Electrolytes Gastrointestinal Infection Medication and Blood Products

The patient with angina and claudication with walking is prescribed isosorbide dinitrate (Isordil). The nurse bases medication teaching on which understanding of the drug's mechanism of action?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 3
  • Topics: Cardiovascular Medication and Blood Products Patient Education

The nurse is preparing to insert a peripherally inserted central catheter (PICC) into the right upper extremity. The goal of the procedure is for the tip to terminate in which location?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 5
  • Topics: Cardiovascular Routes of Administration

The 7-year-old child with pica is brought to the emergency room (ER) with decreased level of consciousness after ingesting lead paint. His blood lead level (BLL) is determined to be 72 mcg/dL. The nurse prepares to administer which medication?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 7
  • Topics: Disease Prevention Growth & Development Health Screening Lifestyle Choices and High Risk Behavior Neurology Health Promotion Intracranial Regulation Laboratory Studies Medication and Blood Products Pediatrics Routes of Administration

The nurse holds the dose of propranolol and contacts the provider for which vital sign?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 5
  • Topics: Cardiovascular Disease Prevention Communication & Documentation Health Care Quality Medication and Blood Products

The nurse is teaching the patient who has been prescribed propranolol. Which statement by the patient indicates an understanding of the teaching?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Cardiovascular Communication & Documentation Disease Prevention Endocrine Medication and Blood Products Patient Education

The nurse is providing medication instructions for iron supplements to a patient with anemia. Which information is included?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 5
  • Topics: Gastrointestinal Hematology/Oncology Communication & Documentation Elimination Medication and Blood Products Patient Education Routes of Administration

Which medication is used to treat epilepsy?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 1
  • Topics: Medication and Blood Products Neurology Intracranial Regulation

Which medication is a beta blocker?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 1
  • Topics: Cardiovascular Medication and Blood Products Routes of Administration

Which medication is an anxiolytic?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 1
  • Topics: Medication and Blood Products Mental Health Disorders Intracranial Regulation Neurology Psychiatric Medications

A nurse reviews a patient’s medication list and recognizes an antibiotic. Which medication does the nurse recognize as an antibiotic?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 1
  • Topics: Medication and Blood Products

Which medication is a hypoglycemic agent?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 1
  • Topics: Endocrine Medication and Blood Products

Which medication is a member of the biologic pharmacologic class?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 2
  • Topics: Medication and Blood Products Hematology/Oncology Immunity Inflammation

The 35-year-old woman is interested in starting hormonal birth control. Which characteristic, if found in the patient's medical record, indicates the patient requires an alternative form of contraceptive?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 5
  • Topics: Endocrine Cardiovascular Communication & Documentation Disease Prevention Health Promotion Hematology/Oncology Inflammation Lifestyle Choices and High Risk Behavior Medication and Blood Products Sexuality and Reproduction

Which comorbidities increase the risk for refeeding syndrome in the chronically ill patient who is started on total parenteral nutrition (TPN)? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 8
  • Topics: Acid-Base Gastrointestinal Elimination Fluid and Electrolytes Hematology/Oncology Immunity Infection Inflammation Routes of Administration

The patient has come to the emergency department by ambulance for presumed heroin overdose. The nurse expects the patient to have received which medication in the field?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 3
  • Topics: Lifestyle Choices and High Risk Behavior Medication and Blood Products Neurology Communication & Documentation

An acutely intoxicated child is brought to the ED because his parents suspect he has consumed antifreeze. The nurse anticipates administering which medication?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 7
  • Topics: Lifestyle Choices and High Risk Behavior Medication and Blood Products Neurology

The patient with a severe peanut allergy was inadvertently exposed to peanuts at work. Dyspnea persists despite the patient using the epinephrine autoinjector and emergency medical services was contacted. Which concentration of epinephrine does the first responder prepare for intramuscular injection?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Cardiovascular Respiratory Routes of Administration Immunity Inflammation Medication and Blood Products Nursing Interventions

Which symptoms, if present in the patient receiving a blood transfusion, indicate the patient is experiencing an acute hemolytic transfusion reaction? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 8
  • Topics: Hematology/Oncology Medication and Blood Products Assessment Cardiovascular Communication & Documentation Inflammation

The female patient’s hypertension is controlled with reduced sodium intake and enalapril and has no other health problems. Abdominal weight gain is noted at the patient’s regular checkup and a human chorionic gonadotropin test is positive. Further testing reveals the patient is 32 weeks pregnant. Which assessment is most important for the safety of the fetus in relation to the enalapril?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 9
  • Topics: Cardiovascular Labor and Delivery Prenatal Care

The patient has been prescribed enalapril and spironolactone for the treatment of hypertension. The nurse is providing medication education to the patient regarding diet. Which food, if selected by the patient, indicates a need for further teaching?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 5
  • Topics: Acid-Base Cardiovascular Communication & Documentation Disease Prevention Lifestyle Choices and High Risk Behavior Fluid and Electrolytes Patient Education

The nurse prepares the nursing student for the administration of which short-acting cardiovascular drug that can be used to help maintain the patient’s ventricular function after cardiac surgery?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Cardiovascular Communication & Documentation

The nurse anticipates administering which medications to the patient with meningitis? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 8
  • Topics: Cardiovascular Disease Prevention Neurology Infection Inflammation Intracranial Regulation Medication and Blood Products

The nurse is planning care for the patient receiving adalimumab. Which nursing intervention does the nurse utilize to prevent complications of the medication?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 8
  • Topics: Communication & Documentation Disease Prevention Assessment Hematology/Oncology Immunity Infection Inflammation Medication and Blood Products

The nonverbal patient is improving in the intensive care unit following a motor vehicle accident; as such, the continuous hydromorphone infusion is being weaned according to a schedule. The nurse provides education to the patient’s guardian about which signs and symptoms that the pain medicine is being weaned too quickly? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 7
  • Topics: Communication & Documentation Neurology Health Promotion Inflammation Intracranial Regulation Medication and Blood Products Patient Education Respiratory

The 14-year-old patient was admitted following surgical reduction of an open femur fracture. The patient, who has reported good pain control with the patient-controlled analgesia (PCA) pump, is sleeping peacefully. During hourly rounding, the nurse observes the parent press the button to administer the bolus of pain medication. Which action by the nurse is appropriate?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Communication & Documentation Routes of Administration Health Care Ethics, Law, and Policy Health Promotion Inflammation Intracranial Regulation Medication and Blood Products Nursing Interventions Patient Education Pediatrics

The patient is receiving alefacept. Which finding indicates the patient is having the desired response to therapy?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 9
  • Topics: Hematology/Oncology Immunity Inflammation Medication and Blood Products Tissue Integrity

The nurse advocates for the use of secukinumab in which patient?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 10
  • Topics: Communication & Documentation Disease Prevention Health Promotion Immunity Infection Inflammation Medication and Blood Products Musculoskeletal Routes of Administration Tissue Integrity

The patient receiving patient-controlled analgesia (PCA) with morphine is found to be sleeping deeply and minimally responsive. Which action does the nurse take first?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Delegation, Prioritization and Leadership Respiratory Routes of Administration Assessment Cardiovascular Intracranial Regulation Medication and Blood Products Nursing Interventions

The LPN/LVN informs the supervising RN, “I didn’t realize until after administering the medication, but I was supposed to give the patient a half tablet of levothyroxine; I gave him a whole tablet.” Which action does the nurse take first?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Cardiovascular Communication & Documentation Delegation, Prioritization and Leadership Endocrine Health Care Ethics, Law, and Policy Health Care Quality Medication and Blood Products

The nurse is setting up a patient-controlled analgesia (PCA) for the infusion of hydromorphone. Which drugs does the nurse have readily available? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 4
  • Topics: Neurology Respiratory Routes of Administration

The nurse is planning care for the patient who will undergo hip replacement surgery in a month. When is the best time to provide teaching about the use of a patient-controlled analgesia (PCA) pump?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 3
  • Topics: Communication & Documentation Routes of Administration Health Care Quality Health Promotion Medication and Blood Products Nursing Interventions Patient Education

The 3.2 kg patient with persistent pulmonary hypertension of the newborn (PPHN) has the following order: Infuse norepinephrine 0.05 mcg/kg/min IV and titrate q15 minutes by 0.05 mcg/kg/min to maintain mean arterial pressure between 45 and 55 mm Hg. Overnight, the norepinephrine had been titrated to 0.25 mcg/kg/min for persistent hypotension. At 0900, the MAP rose to 62 mm Hg and the nurse decreased the infusion from 0.25 mcg/kg/min to 0.20 mcg/kg/min. At 0905, the patient’s blood pressure fell to 42 mm Hg. Which action does the nurse take first?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 7
  • Topics: Cardiovascular Delegation, Prioritization and Leadership Medication and Blood Products Nursing Interventions Routes of Administration Weight-Based Dosing

The patient has experienced an extravasation of norepinephrine in the right forearm. It is cool to the touch, firm, and pale. Distal to peripheral pulses are not well felt and the fingertips are dusky. Which order does the nurse clarify with the provider?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 7
  • Topics: Cardiovascular Communication & Documentation Medication and Blood Products Nursing Interventions Routes of Administration Tissue Integrity

The nurse assesses the peripheral IV site of the patient who is receiving norepinephrine, which was started for profound, life-threatening hypotension and finds the hand to be firm to the touch, cool, and pale. Which action does the nurse take?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 8
  • Topics: Cardiovascular Routes of Administration Medication and Blood Products Nursing Interventions Tissue Integrity

The asymptomatic patient tested positive for Neisseria gonorrhoeae during routine screening for sexually transmitted infections (STI). The nurse anticipates administering which medications? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 6
  • Topics: Infection Laboratory Studies Lifestyle Choices and High Risk Behavior Medication and Blood Products Nursing Interventions Routes of Administration Sexuality and Reproduction

The 32-weeks-pregnant woman who presents with genital lesions is diagnosed with herpes simplex virus-2. The nurse prepares a patient information handout for which medication for this patient?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 3
  • Topics: Disease Prevention Labor and Delivery Prenatal Care Communication & Documentation Health Promotion Lifestyle Choices and High Risk Behavior Medication and Blood Products Nursing Interventions Patient Education Routes of Administration Sexuality and Reproduction Tissue Integrity

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