The patient with cellulitis may have symptoms caused by a methicillin-resistant strain of Staphylococcus aureus. Therefore, the patient who is least at risk for complications of a MRSA infection should be paired with this patient until the causative organism is determined. The patient admitted for COPD exacerbation is the most appropriate patient to pair with this individual. The patient with methicillin-resistant Staphylococcus pseudintermedius, a common canine microorganism seen only in severely immunocompromised individuals, should be prevented from contact with anyone who has an infection. The 32-year-old patient who will be undergoing surgery for a brain aneurysm in the morning should not come in contact with individuals with active infections, especially one that might be caused by a drug-resistant organism, to decrease the patient’s risk for central nervous system infection. The patient with DKA due to gastroenteritis should not be roommates with another individual with an infectious disease to prevent sharing of organisms between individuals with immune systems that are weakened by infection.