Penicillin G is the drug of choice for syphilis, even in patients who have had previous anaphylactic reactions to medications in the penicillin family. Other medications are less effective than penicillin. The correct nursing action is to obtain the hospital policy on penicillin desensitization procedure and obtain the necessary orders. The patient will be premedicated with diphenhydramine and a steroid, but the nurse does not just administer the medication immediately after. Although the dose will be divided into smaller doses for the desensitization procedure, the dose is not divided throughout the day.