The nurse first clamps the peripherally inserted central catheter (PICC) line to prevent further air entry. Then, the nurse places the patient in left lateral Trendelenburg to guide the air into the right atrium. From there, the air will be dispersed into the pulmonary artery, which is safer then heading to the brain or coronaries. The nurse then applies oxygen to improve patient comfort and oxygen saturation. Once the nurse has performed these tasks to ensure safety of the patient, the nurse calls for help and further management.