Pharmacological and Parenteral Therapies

The nurse must be able to safely administer medications and other therapeutics as well as differentiate between intended effects and side effects. The Pharmacological and Parenteral Therapies subcategory of the NCLEX-RN exam covers topics related to medication administration, injections, and infusions. This section covers blood product administration, dosage calculating, venous access, and other issues pertinent to medication and parenteral therapies.

The nurse is examining the waveform produced by central venous pressure (CVP) catheter. At which point on the waveform does atrial relaxation occur?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 8
  • Topics: Cardiovascular Assessment

The nurse is examining the waveform produced by central venous pressure (CVP) catheter. Ventricular contraction occurs at which point of the waveform?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 8
  • Topics: Cardiovascular Assessment

The nurse is examining the waveform produced by central venous pressure (CVP) catheter. Tricuspid valve opening is reflected at which point on the waveform?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 8
  • Topics: Cardiovascular Assessment

The nurse is examining the waveform produced by central venous pressure (CVP) catheter. Passive filling of the atria occurs at which point on the waveform?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 8
  • Topics: Cardiovascular Assessment

The nurse is reviewing the medication list of the patient who wishes to become pregnant. One of the medications is listed as Category X. The nurse knows this medication poses which level of risk to the fetus?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 2
  • Topics: Medication and Blood Products Prenatal Care Assessment Health Care Ethics, Law, and Policy Health Care Quality Health Promotion Health Screening Nursing Interventions Sexuality and Reproduction

The patient with diabetes insipidus has been prescribed vasopressin. The nurse instructs the student nurse about which characteristic of the medication?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 4
  • Topics: Endocrine Medication and Blood Products Routes of Administration Elimination Fluid and Electrolytes Nursing Interventions

The provider orders albumin for a patient with traumatic amputation and hemorrhage. Which patient characteristic prompts the nurse to clarify the order with the provider?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 3
  • Topics: Crisis Management Medication and Blood Products Cardiovascular Communication & Documentation Delegation, Prioritization and Leadership Immunity Inflammation Routes of Administration

Which statement describes the mechanism of action of erenumab (Aimovig)?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 2
  • Topics: Inflammation Intracranial Regulation Medication and Blood Products Neurology

About which expected side effect does the nurse educate the patient prescribed colchicine for treatment of gout?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 4
  • Topics: Medication and Blood Products Neurology Communication & Documentation Elimination Inflammation Musculoskeletal Patient Education

The patient with seizures has been prescribed carbamazepine (Tegretol). Which medication, if found on the patient's current medication list, prompts the nurse to hold the medication and contact the provider for clarification?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 7
  • Topics: Medication and Blood Products Neurology Communication & Documentation Hematology/Oncology Immunity Infection Inflammation

The patient with arteriovenous malformation who takes a monoamine oxidase inhibitor for depression develops an upper respiratory infection. The nurse requests a prescription for which medication?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 10
  • Topics: Cardiovascular Communication & Documentation HEENT Neurology Intracranial Regulation Medication and Blood Products Routes of Administration

The 5-year-old patient has been prescribed phenytoin for the treatment of seizures. Which statement by the patient’s mother prompts the nurse to contact the provider for an alternative prescription?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 9
  • Topics: Communication & Documentation Neurology Routes of Administration

The patient presents to the emergency department (ED) with flu-like symptoms and mucocutaneous erythematous rash and bullae formation over 38% of the body. The nurse asks the patient if which medications had been taken in the last month? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 8
  • Topics: Communication & Documentation Neurology Assessment Immunity Inflammation Intracranial Regulation Medication and Blood Products Tissue Integrity

The nurse is administering intravenous fluids to the patient with toxic epidermal necrolysis. Which parameters are most helpful to assess when determining the appropriate fluid rate for the patient?

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 9
  • Topics: Acid-Base Communication & Documentation Routes of Administration Elimination Fluid and Electrolytes Immunity Inflammation Medication and Blood Products Nursing Interventions Tissue Integrity

The patient presents to the women’s health clinic with complaints of itching and burning on urination with a white, curd-like vaginal discharge. The provider reports the cervix appears normal on exam. The nurse prints patient information for which medication course?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Infection Medication and Blood Products Patient Education Routes of Administration Sexuality and Reproduction

The nurse is answering questions regarding a new prescription of a monoamine oxidase type B inhibitor (MAOI-B) for the patient recently diagnosed with Parkinson's disease. Which reminders does the nurse include in teaching? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 6
  • Topics: Communication & Documentation Disease Prevention Medication and Blood Products Psychiatric Medications

The nurse questions which drug prescribed to a patient also receiving carbamazepine for psychomotor seizures?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 7
  • Topics: Communication & Documentation Medication and Blood Products Neurology

The registered nurse is observing the licensed practical/vocational nurse (LPN/LVN) administering pantoprazole during morning medication rounds. Which action by the LPN/LVN prompts the nurse to intervene and provide additional education?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Communication & Documentation Delegation, Prioritization and Leadership Gastrointestinal Medication and Blood Products Routes of Administration

The nurse has received orders for the patient admitted following a hemorrhagic stroke and clarifies orders for which medications? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 7
  • Topics: Cardiovascular Communication & Documentation HEENT Hematology/Oncology Neurology Intracranial Regulation Medication and Blood Products

The nurse is preparing the patient for an ophthalmoscopic exam in which cyclopentolate drops must be instilled to allow for better visualization of the retina. Which characteristics, if present in the patient’s medical history, prompt the nurse to hold the drops and contact the provider for further instruction? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 7
  • Topics: Communication & Documentation Health Screening HEENT Routes of Administration Cardiovascular

Which instruction does the nurse give the patient prior to administering cyclopentolate eye drops?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 7
  • Topics: Communication & Documentation Health Screening HEENT Routes of Administration Cardiovascular

The nurse is educating the patient on self-administering antibiotic eye drops. Which instruction does the nurse include?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Communication & Documentation HEENT Routes of Administration

Which instruction does the nurse give to the patient who is prescribed short-acting insulin? 

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 3
  • Topics: Medication and Blood Products Endocrine

The nurse is providing medication teaching to the mother of a 4-year-old patient with recurrent otitis media infections who requires daily instillation of antibiotic drops into the ear. Which action indicates effective teaching?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Communication & Documentation Growth & Development HEENT Routes of Administration Health Promotion Infection Inflammation Medication and Blood Products Nursing Interventions Patient Education Pediatrics

The nurse is educating the 2-year-old patient’s parents on how to instill ear drops to treat acute otitis media. Which statement indicates a need for further teaching?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 7
  • Topics: Communication & Documentation Disease Prevention Growth & Development HEENT Routes of Administration Health Care Quality Health Promotion Infection Inflammation Medication and Blood Products Nursing Interventions Patient Education Pediatrics

The patient has been prescribed amoxicillin for the treatment of sinusitis. The patient states, “I thought I just had a cold. I don’t want to take antibiotics for a cold.” Which response by the nurse is most appropriate?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 7
  • Topics: Communication & Documentation HEENT Health Promotion Immunity Infection Inflammation Intracranial Regulation Medication and Blood Products Patient Education Respiratory Routes of Administration

The patient with palpitations and sharp chest pain that is worse with inspiration than expiration is brought to the emergency department (ED). Upon auscultation of heart sounds, the nurse notes a scratching noise, like leather rubbing together. Breath sounds are clear and equal bilaterally. Complete blood count is notable for leukocytosis; cardiac enzymes are within normal limits. The nurse prepares the patient for which treatment?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 10
  • Topics: Cardiovascular Inflammation Medication and Blood Products Routes of Administration

The 5-year-old child is brought to the emergency department (ED) after a fall at school that has resulted in a broken wrist. The nurse notes the child is thin, with curved femurs and kyphosis. Metaphyseal fraying and cupping is noted on x-ray of the wrist. There is evidence of old fractures that healed poorly, as if they hadn’t been set properly. Upon review of the patient’s medical history, it does not appear that the patient has received ongoing well-child care. After laboratory evaluation, the child is diagnosed with rickets. The nurse prepares information on which medication for the family?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 7
  • Topics: Growth & Development Musculoskeletal Routes of Administration

Following traumatic bilateral leg amputations, the 5-year-old child requires a STAT blood transfusion to treat hemorrhagic shock. The child's blood type is unknown. Which action is most appropriate? 

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Crisis Management Delegation, Prioritization and Leadership Medication and Blood Products Pediatrics Cardiovascular Health Care Ethics, Law, and Policy Health Care Quality Nursing Interventions

Which statement is true regarding the administration of intravenous potassium?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 4
  • Topics: Acid-Base Cardiovascular Assessment Fluid and Electrolytes Medication and Blood Products Routes of Administration

Which information does the nurse provide to the patient with epilepsy who has been prescribed phenytoin?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 4
  • Topics: Medication and Blood Products Neurology Communication & Documentation HEENT Intracranial Regulation Patient Education

Which is an example of hypertonic intravenous (IV) fluid?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 2
  • Topics: Acid-Base Fluid and Electrolytes Medication and Blood Products Routes of Administration

A six-year-old child presents to a primary care appointment with curved tibias and fibulas, protruding forehead, pigeon chest, and protruding abdomen. Which vitamin deficiency does the nurse immediately suspect?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 9
  • Topics: Development Disease Prevention Health Promotion Musculoskeletal Pediatrics Routes of Administration

The patient has been receiving sildenafil 5 mg by mouth, three times daily. Which assessment finding indicates the drug has had the intended effect?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 9
  • Topics: Cardiovascular Assessment Medication and Blood Products Respiratory Routes of Administration

The nurse is reviewing the chart of a patient recently admitted to the hospital. The patient’s medication review includes bosentan, glyburide, praziquantel, and ergotamine. The nurse expects to observe which symptom in the patient?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 10
  • Topics: Cardiovascular Endocrine Medication and Blood Products Neurology Respiratory

The patient newly diagnosed with idiopathic pulmonary arterial hypertension is prescribed bosentan. The result of which test is most important for the nurse to verify prior to administering the medication?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 10
  • Topics: Cardiovascular Communication & Documentation Disease Prevention Prenatal Care

The patient receiving bosentan therapy for pulmonary arterial hypertension presents to the emergency department (ED) complaining of dyspnea. Which nursing assessment is most important for this patient?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 9
  • Topics: Cardiovascular Respiratory Assessment Communication & Documentation Fluid and Electrolytes Medication and Blood Products Routes of Administration

The patient is prescribed bosentan. Which statement does the nurse include in teaching about this medication?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 5
  • Topics: Cardiovascular Communication & Documentation Respiratory Medication and Blood Products Patient Education

The patient presents to the emergency department (ED) and states, “I don’t know what happened! I was walking and ran into a door with my right shoulder. I closed my right eye and my vision was normal, but when I closed my left eye, I couldn’t see anything at all!” The patient’s assessment is otherwise normal. The nurse reports this to the provider immediately for assessment. Which question is most important for the nurse to ask the patient while waiting for the provider to write orders for treatment?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 10
  • Topics: Cardiovascular Communication & Documentation HEENT Respiratory Acid-Base Assessment Fluid and Electrolytes Health Care Quality Health Promotion Health Screening Medication and Blood Products Routes of Administration

Which is the drug of choice for treatment of Raynaud syndrome?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 6
  • Topics: Cardiovascular Respiratory Delegation, Prioritization and Leadership Medication and Blood Products Tissue Integrity

The patient being treated for seizures has developed Raynaud’s phenomenon. The nurse anticipates the provider to order which medication for this patient?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 10
  • Topics: Cardiovascular Neurology Medication and Blood Products

The patient receiving which medication is most likely to also require a prescription for miconazole?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 9
  • Topics: Endocrine Infection Tissue Integrity Elimination Health Care Quality Health Promotion Health Screening Immunity Nursing Interventions

The 74-year-old otherwise healthy patient presents to the clinic complaining of severe pain and burning of the skin over the right flank. Upon assessment, the nurse notes two lines of vesicles that curve laterally away from the spine on the right side. The nurse provides which instruction to the patient regarding treatment?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 10
  • Topics: Communication & Documentation Immunity Infection Inflammation Patient Education Tissue Integrity Disease Prevention Health Promotion Medication and Blood Products Routes of Administration

The 15-year-old emancipated minor patient who weighs 32 kg presents to the emergency department with fever, malaise, cervical lymphadenopathy, and severe throat pain that was not preceded by an upper respiratory infection. The nurse anticipates providing teaching about which prescription?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 10
  • Topics: Communication & Documentation Disease Prevention HEENT Immunity Infection Inflammation Patient Education

The 12-year-old child is brought to the emergency room after being bitten by a family friend’s tarantula. The child is healthy and has received all scheduled vaccinations. Which medication must be given as soon as possible?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 9
  • Topics: Disease Prevention Immunity Infection Inflammation Tissue Integrity

The patient seeking medical care for a spider bite asks the nurse why the Diphtheria, Tetanus, and Pertussis (DTaP) vaccine has been prescribed. Which response by the nurse is most appropriate?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 9
  • Topics: Communication & Documentation Disease Prevention Immunity Infection Inflammation Patient Education

The 32-year-old female patient (60 kg) is brought via ambulance to the emergency department following a water drinking competition. The patient has a Glasgow Coma score of 6, oxygen saturation of 94% on room air, heart rate of 62 bpm, and respiratory rate of 16 breaths per minute. The nurse anticipates administering which medication?

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 10
  • Topics: Delegation, Prioritization and Leadership Fluid and Electrolytes Intracranial Regulation Lifestyle Choices and High Risk Behavior Neurology Routes of Administration Endocrine Medication and Blood Products

The nurse anticipates administering cobalamin and folic acid to the patient presenting with which symptoms? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 8
  • Topics: Gastrointestinal Hematology/Oncology Tissue Integrity Assessment Laboratory Studies Medication and Blood Products Neurology

The nurse informs the patient beginning pharmacological therapy for prostate cancer to anticipate which additional changes? Select all that apply.

  • Question Type:   Multiple Choice - Select All
  • Difficulty: 9
  • Topics: Endocrine Hematology/Oncology Patient Education Sexuality and Reproduction

The 3-year-old patient with acute pyelonephritis has the following orders:  Medications: 8 mg/kg ciprofloxacin IV q8h  Activity level: ambulatory as tolerated  Intravenous fluids: Infuse D5W with 0.25% NaCl via peripheral IV at 50 mL/h  Diet: Normal   The nurse is coordinating care for the patient with the unlicensed assistive personnel. Which statement by the UAP prompts further education by the nurse? 

  • Question Type:   Multiple Choice - Select One
  • Difficulty: 10
  • Topics: Communication & Documentation Delegation, Prioritization and Leadership Elimination Growth & Development Health Care Quality Infection Mobility Tissue Integrity

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