The patient newly diagnosed with idiopathic pulmonary arterial hypertension is prescribed bosentan. The result of which test is most important for the nurse to verify prior to administering the medication?

Human chorionic gonadotropin. Bosentan is contraindicated in pregnancy due to significant teratogenicity; therefore, it is most important that the nurse verify a negative human chorionic gonadotropin test in the patient prior to administering it. It can also cause hepatotoxicity, so serum aminotransferase levels must be obtained for a baseline and then monitored regularly. Although review of the echocardiogram results may be helpful to verify the necessity of bosentan, this is not the most critical test to review. Bosentan does not cause renal failure, so BUN and creatinine are less important to review.

The patient newly diagnosed with idiopathic pulmonary arterial hy...

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Pharmacological and Parenteral Therapies
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Category: Pharmacological and Parenteral Therapies
Difficulty: 10

Topics: Cardiovascular Communication & Documentation Disease Prevention Prenatal Care

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