The patient with well-controlled chronic obstructive pulmonary disorder presents with a 3 day history of increased cough with sputum production, fever, and malaise. Upon assessment, breath sounds are clear after coughing and the patient appears to breathe comfortably with no retractions or nasal flaring. His chest x-ray is clear and his screening complete blood count is largely normal, with exception of a white blood cell count of 16. The nurse anticipates the provider to order which medication(s)? Select all that apply.

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Azithromycin. The patient has bronchitis without COPD exacerbation; azithromycin is the drug of choice. If the patient did not have COPD, supportive therapy rather than antibiotics would be the treatment of choice. Ceftriaxone and azithromycin together would be appropriate to treat community-acquired pneumonia, but the patient&rsquo;s x-ray is clear, which rules out pneumonia. Vancomycin is not the appropriate choice for bronchitis. Levofloxacin is not appropriate because it should be reserved for more serious infections to limit resistance. Amoxicillin-clavulanate is used to treat aspiration pneumonia, not bronchitis.

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