Infusion of contrast into a compromised IV site can result in soft tissue necrosis. Therefore, the nurse must ensure the patency of the IV prior to administering the medication. The long-held belief that there is an association between shellfish allergy and an allergy to contrast has been proven to be a myth. Although it is important to know about the patient’s claustrophobia, this can be treated with an anxiolytic or sedative. The patient’s DVT history is important but not as vital as the patency of the IV catheter.