The adolescent diagnosed with schizophrenia who demonstrates increasing apathy, poor hygiene, and worsening cognitive functioning may be experiencing deterioration of the frontal cortex. Schizophrenia does not necessarily cause progressive worsening like Alzheimer’s or Parkinson’s. Accusing the patient of spitting out medicine is not helpful as the deterioration of the frontal lobe occurs despite medication compliance. Although the patient might need an increased dose or an additional drug, this does not explain why the patient’s symptoms are worsening.