Clozapine, an atypical antipsychotic, can have severe adverse effects. The most dangerous side effect is agranulocytosis, which can lead to immunocompromise. Therefore, the most important lab test to ensure safety is the CBC to monitor the patient’s white blood cell count. Clozapine can cause metabolic disturbances such as weight gain, diabetes, and hyperlipidemia. The patient will also require frequent lipid panel and glycosylated hemoglobin monitoring, but these are less life-threatening than agranulocytosis and subsequent immunocompromise.