The 40-year-old patient has been diagnosed with early-onset Familial Alzheimer disease (FAD) and asks the nurse how likely it is that her children will have the disorder. Which response by the nurse is appropriate?

“Each of your children has a 50% chance of having one of the genes responsible for FAD.”. Familial Alzheimer disease is a rare autosomal dominant disorder that is caused by one of three genes on chromosome 21. Because it is autosomal dominant and rare, it can be assumed that the father does not have the disorder. Therefore, each child has a 50% chance of having inherited the gene responsible for FAD. It is not an X-linked disorder, so it is not limited to the male children. As an autosomal dominant disorder, there are no carriers – they either have the affected gene or do not.

The 40-year-old patient has been diagnosed with early-onset Famil...

Category: Psychosocial Integrity
Difficulty: 7

Topics: Communication & Documentation Genetics Mental Health Disorders

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